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翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク (Methionine synthase) reductase ： ウィキペディア英語版 (Methionine synthase) reductase In enzymology, a (synthase ) reductase () is an enzyme that catalyzes the chemical reaction :2 (synthase )-methylcob(I)alamin + 2 S-adenosylhomocysteine + NADP+ $\backslash rightleftharpoons$ 2 (synthase )-cob(II)alamin + NADPH + H+ + 2 S-adenosyl-L-methionine The 3 products of this enzyme are methionine synthase-methylcob(I)alamin, S-adenosylhomocysteine, and NADP+, whereas its 4 substrates are methionine synthase-cob(II)alamin, NADPH, H+, and S-adenosyl-L-methionine. Over time, the cob(I)alamin cofactor of methionine synthase becomes oxidized to cob(II)alamin rendering the enzyme inactive. Regeneration of functional enzyme requires reductive methylation via a reaction catalyzed by (methionine synthase) reductase in which S-adenosylmethionine is utilized as a methyl donor. This enzyme belongs to the family of oxidoreductases, to be specific those oxidizing metal ion with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is (synthase )-methylcob(I)alamin,S-adenosylhomocysteine:NADP+ oxidoreductase. Other names in common use include methionine synthase cob(II)alamin reductase (methylating), methionine synthase reductase, (synthase )-cobalamin methyltransferase (cob(II)alamin, and reducing). It employs one cofactor, flavoprotein. ==References== * * * 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「(Methionine synthase) reductase」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.